First released in 1998 UTRdb, has become a reference resource for the scientific community, thanks also to the data curation and support we have provided.
The last published update of UTRdb was in 2010, and since then, the database has been maintained and kept accessible.
UTRdb is still very used, as proven by the remarkable number of citations, even if the last significant update was in 2015.
We have completely revised and updated the database structure and content, featuring novel functionalities.
The new version of UTRdb hosts sequences and annotations from more than 570 organisms for a total of 26,098,657 annotated UTRs.
All the UTRdb entries have been generated according to the sequence data and gene annotations available on the Ensembl databases.
UTRdb entries are enriched with specialized annotations, which include occurrences of regulatory elements (from RFAM), highly conserved blocks (from PhastCons),
Internal Ribosome Entry Sites (from IRESite), experimentally validated miRNAs targets (from TarBase), repetitive elements, polyA signals, RNA editing sites (from Rediportal),
polymorphisms, and others.
Many of these annotations can also be used as filters to build queries for UTRdb.
This updated version of UTRdb also includes a custom gene view module to display UTRs in their genomic context and a graphical representation of their annotations.